NetProTM is a comprehensive bio-molecular interaction database, which comprises of protein-protein interactions and protein-small molecule interactions.
NetProTM currently has more than 320,000+ manually curated unique interactions from scientific literature. The knowledgebase facilitates navigation through the complex human biological pathways map including metabolic processes and cellular signaling.
The strength of NetProTM lies in the manual curation of the interactions and in the content granularity. The knowledgebase has been extensively normalized with standard terms for both the interacting molecules and the type of interactions.
Exhaustive controlled vocabulary largely sourced from public domain makes it easier for the knowledgebase to be integrated to other proprietary databases.
The knowledgebase can be specifically queried and filtered for various fields like molecules, molecule types, species, interaction terms, interaction type, cellular localization, pathway, disease etc.
Disease related information pertaining to the interactions is available which could be a mutation detail, expression profile or any other significant properties of the interacting molecule with respect to the disease.
MINETM a Java based visualization tool developed by Molecular Connections, could be used for querying, filtering and analyzing NetProTM data.