Case Studies
August, 2009 - Probable interaction networks involved in pathology of Alzheimer’s disease: predicting targets and therapeutic agents-NetProTM based study.
Objective: To highlight the application of NetProTM in predicting interaction networks, potential targets and therapeutic agents for specific pathological conditions using high throughput data
July, 2009 - Using XTractor to investigate the application of RNAi in exploring p53 interactions and processes in cancer therapy.
Objective: To elucidate the application of RNAi in understanding the interactions of p53 and explore the common processes involved in RNAi cancer treatment
July, 2009- Exploring the role of HDACs in Neoplasms and use of their inhibitors in Cancer Treatment.
Objective: To find out the frequently occurring neoplasms associated with HDAC-altered expression, drugs being used as HDAC inhibitors, and the processes encompassed by drugs to inhibit HDAC.
June, 2009 - Studying the Interrelationships between PPARs,Type 2 Diabetes Mellitus and Rosiglitozone using XTractor.
Objective: To explore the association of PPARs with type 2 diabetes mellitus, find the drugs interacting with type 2 diabetes mellitus via the PPARs and also discover the common protein player between Rosiglitazone, a PPARG agonist and type 2 diabetes mellitus.
June, 2009 - Identifying common GPCRs associated with hypoglycemia and diabetes.
Objective: To explore the GPCR types associated with hypoglycemic drugs, find the association of the above GPCRs with diabetes and also uncover the common GPCRs between diabetes and hypoglycemic drugs.
May, 2009 - Understanding Pharmacologic actions, protein interactions and toxicity studies of Fluvoxamine using XTractor.
Objective: To understand the Pharmacologic actions, protein interactions and toxicity of Fluvoxamine
May, 2009 - Understanding Pharmacologic actions, protein interactions and toxicity studies of Amitriptyline using XTractor.
Objective: To understand the Pharmacologic actions, protein interactions and toxicity of Amitriptyline
April, 2009 - What's common across Breast cancer, Lung cancer, Colon Cancer and Ovarian Cancer?
Objective: To track the common entities across Breast cancer, Lung cancer, Colon Cancer and Ovarian Cancer
March, 2009 - Understanding Pathology and Mechanisms of Dengue Virus Infections using XTractor.
Objective: To eucidate Pathology and Mechanism of Dengue Virus Infections
Feb, 2009 - Understanding Multiple Target preferences for Imatinib(Gleevec) with XTractor.
Feb, 2009 - Tracking common gene polymorphisms across multiple Diseases with XTractor.
