Case Studies

Probable interaction networks involved in pathology of Alzheimer’s disease: predicting targets and therapeutic agents-NetPro^TM based study.
Objective: To highlight the application of NetPro^TM in predicting interaction networks, potential targets and therapeutic agents for specific pathological conditions using high throughput data

Using XTractor to investigate the application of RNAi in exploring p53 interactions and processes in cancer therapy.
Objective: To elucidate the application of RNAi in understanding the interactions of p53 and explore the common processes involved in RNAi cancer treatment

Exploring the role of HDACs in Neoplasms and use of their inhibitors in Cancer Treatment.
Objective: To find out the frequently occurring neoplasms associated with HDAC-altered expression, drugs being used as HDAC inhibitors, and the processes encompassed by drugs to inhibit HDAC.

Studying the Interrelationships between PPARs,Type 2 Diabetes Mellitus and Rosiglitozone using XTractor.
Objective: To explore the association of PPARs with type 2 diabetes mellitus, find the drugs interacting with type 2 diabetes mellitus via the PPARs and also discover the common protein player between Rosiglitazone, a PPARG agonist and type 2 diabetes mellitus.

Identifying common GPCRs associated with hypoglycemia and diabetes.
Objective: To explore the GPCR types associated with hypoglycemic drugs, find the association of the above GPCRs with diabetes and also uncover the common GPCRs between diabetes and hypoglycemic drugs.

Understanding Pharmacologic actions, protein interactions and toxicity studies of Fluvoxamine using XTractor.
Objective: To understand the Pharmacologic actions, protein interactions and toxicity of Fluvoxamine

Understanding Pharmacologic actions, protein interactions and toxicity studies of Amitriptyline using XTractor.
Objective: To understand the Pharmacologic actions, protein interactions and toxicity of Amitriptyline

What's common across Breast cancer, Lung cancer, Colon Cancer and Ovarian Cancer?
Objective: To track the common entities across Breast cancer, Lung cancer, Colon Cancer and Ovarian Cancer

Understanding Pathology and Mechanisms of Dengue Virus Infections using XTractor.
Objective: To eucidate Pathology and Mechanism of Dengue Virus Infections

Understanding Multiple Target preferences for Imatinib(Gleevec) with XTractor.

Tracking common gene polymorphisms across multiple Diseases with XTractor.